Bio-Oss^® Natural Bone Grafting Material

Bio-Oss® natural bone mineral offers predictable results which have been proven through years of clinical experience and extensively documented in published scientific literature.

Bio-Oss^®: Morphology like human bone

The trabecular architecture and fine crystalline structure of the natural bone in Bio-Oss® are preserved through a patented manufacturing process, resulting in an exceptional osteoconductive matrix.

1. Clot stabilization facilitated by Bio-Oss® interconnecting macro and micropores.
2. Revascularization, migration of osteoblasts (purple) and in-growth of woven bone (yellow) is enhanced by Bio-Oss® scaffolding.
3. Lamellar bone and Bio-Oss® are successfully integrated after approximately six months. Bio-Oss® is included in the natural physiologic remodeling process (osteoclasts - Blue).
   
   

Advantages of Bio-Oss^®

• Superior handling characteristics made possible by the large hydrophilic inner surface area similar to human bone.
• Promotes revascularization and clot stabilization, due to its interconnecting macro and micropores.
• Facilitates bone formation by providing an exceptional osteoconductive scaffolding which results from the retention of the natural porous architecture and trabeculation of human cancellous bone.
• Effective space maintenance, and when integrated, provides mechanical strength and stiffness due to retention of the natural mineral content.
• Optimal integration with patient's own bone aided by a chemical composition analogous to human bone with fewer hydroxyl and more carbonate groups than most synthetic materials.
• Bio-Oss® is integrated during the natural remodelling process of the human bone and slowly resorbed due to small crystallite size which is comparable to human bone.
• Effective bone regeneration that has been clinically and scientifically proven for more than 15 years.
• Bio-Oss® prevents newly formed bone from rapid resorption and leads to a long-term preservation of the bone volume.