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Lynch S, Wisner-Lynch L, Nevins M , Nevins ML. A New Era in Periodontal and Periimplant Regeneration: Use of Growth Factor Enhanced Matrices Incorporating rhPDGF. Compend Contin Educ Dent 2006 Dec; 27: (12):672-679. [ ABSTRACT ]

Belal MH, Watanabe H, Ichinose S, Ishikawa I. A Time-dependant Effect of PDGF-BB on Adhesion and Growth of Cultured Fibroblasts to Root Surfaces. Oral Dis 2006 Nov; 12 (6):543-552. [ ABSTRACT ]

Rosen PS. Using Recombinant Platelet-Derived Growth Factor To Facilitate Wound Healing. Compend Contin Educ Dent 2006 Sept; 27 (9) 520-525. [ ABSTRACT ]

Simion M, Rocchietta I, Kim D, Nevins M, Fiorelline J. Vertical Ridge Augmentation by Means of Deproteinized Bovine Bone Block and Recombinant Human Platelet-Derived Growth Factor- BB: A Histologic Study in a Dog Model. Int J Periodontics Restorative Dent 2006 Oct; 26 (5): 415 - 423. [ ABSTRACT ]

Wisner-Lynch LA. From Passive to Active: Will Recombinant Growth Factor Therapeutics Revolutionize Regeneration? Int J Periodontics Restorative Dent 2006 Oct; 26 (5): 409–411. [ ABSTRACT ]

Sarment DP, Cooke JW, Miller SE, Jin Q, McGuire MK, Kao RT, McClain PK, McAllister BS, Lynch SE, Giannobile WV. Effect of rhPDGF-BB on bone turnover during periodontal repair. J Clin Periodontol 2006; 33:135–140. [ ABSTRACT ]

McGuire MK, Scheyer ET. Comparison of recombinant human platelet-derived growth factor-BB plus beta tricalcium phosphate and a collagen membrane to subepithelial connective tissue grafting for the treatment of recession defects: a case series. Int J Periodontics Restorative Dent 2006 Apr;26(2):127-33. [ ABSTRACT ]

Reynolds MA, Aichelmann-Reidy ME. Platelet-Derived Growth Factor Stimulates Bone Fill and Rate of Attachment Level Gain: Results of a Large Multicenter Randomized Controlled Trial. J Periodontol 2005; 76:2330-2332. [ ABSTRACT ]

Bateman J, Intini G, Margarone J, Goodloe S, Bush P, Lynch S, Dziak R. Platelet-Derived Growth Factor Enhancement of Two Alloplastic Bone Matrices. J Periodontol 2005;76:1833-1841. [ ABSTRACT ].

McGuire MK, Kao RT, Nevins M, Lynch SE. rhPDGF-BB promotes healing of periodontal defects: 24-month clinical and radiographic observations. Int J Periodontics Restorative Dent. 2006 Jun;26(3):223-31. [Erratum 2007; 27:88] [ ABSTRACT ]

Nevins M, Giannobile WV, McGuire MK, Kao RT, Mellonig JT, Hinrichs JE, McAllister BS, Murphy KS, McClain PK, Nevins ML, Paquette DW, Han TJ, Reddy MS, Lavin PT, Genco RJ, Lynch SE. Platelet-derived growth factor stimulates bone fill and rate of attachment level gain: results of a large multicenter randomized controlled trial. J Periodontol. 2005 Dec;76(12):2330-2. [ ABSTRACT ] .

Okuda K, Kawase T, Momose M, Murata M, Saito Y, Suzuki H, Wolff L, Yoshie H. Platelet Rich Plasma Contains High Levels of Platelet-Derived Growth Factor and Transforming Growth Factor-β and Modulates the Proliferation of Periodontally Related Cells In Vitro. J Periodontol 2003;74:849-857. [ ABSTRACT ]

Nevins M, Camelo M, Nevins ML, Schenk R, Lynch SE. Periodontal Regeneration in Humans Using Recombinant Human Platelet-Derived Growth Factor BB (rhPDGF-BB) and Allogeneic Bone. J Periodontol 2003 Sept.;74:1282-1292. [ ABSTRACT ]

Papadopoulos CE, Dereka XE, Vavouraki EN, Vrotsos IA. In vitro Evaluation of the Mitogenic Effect of Platelet-Derived Growth Factor-BB on Human Periodontal Ligament Cells cCltured with Various Bone Allografts. J Periodontol 2003 Apr;74(4):45 1-7. [ ABSTRACT ].

Camelo M, Nevins, ML, Schenk RK, Lynch SE, Nevins M. Periodontal Regeneration Can be Achieved in Human Class II Furcations using Purified Recombinant Human Platelet-Derived Growth Factor BB (rhPDGF-BB) with Bone Allograft. Int J Periodont Rest Dent 2003 June;23:213-225. [ ABSTRACT ]

Kawase T, Okuda K, Wolff LF and Yoshie H. Platelet-rich plasma-derived fibrin clot formation stimulates collagen synthesis in periodontal ligament and osteoblastic cells in vitro. J Periodontol 2003 June;74:858-864. [ ABSTRACT ]

Lee JY, Nam SH, Im SY, Park YJ, Lee YM, Seol YJ, Chung CP, Lee SJ. Enhanced bone formation by controlled growth factor delivery from chitosan-based biomaterials. J Control Release 2002;78:187-97. [ ABSTRACT ]

Zhu Z, Lee CS, Tejeda KM, Giannobile WV. Gene transfer and expression of platelet-derived growth factors modulate periodontal cellular activity. J Dent Res 2001 Mar;80(3):892-7. [ ABSTRACT ]

Parkar MH, Kuru L, Giouzeli M, Olsen I. Expression of growth-factor receptors in normal and regenerating human periodontal cells. Arch Oral Biol 2001 Mar;46(3):275-84. [ ABSTRACT ]

Ivanovski S, Haase HR, Bartold PM. Isolation and characterization of fibroblasts derived from regenerating human periodontal defects. Arch Oral Biol 2001 Aug;46(8):679- 88. [ ABSTRACT ]

Mumford JH, Carnes DL, Cochran DL, Oates TW. Th e effects of platelet-derived growth factor-BB on periodontal cells in an in vitro wound model. J Periodontol 2001 Mar;72(3):331-40. [ ABSTRACT ].


Stephan E, Renjen R, Lynch S, Dziak R. Platelet-Derived Growth Factor Enhancement of a Mineral-Collagen Bone Substitute. J Periodontol 2000;71:1887-1892. [ ABSTRACT ].

Meraw SJ, Reeve CM, Lohse CM, Sioussat TM. Treatment of peri-implant defects with combination growth factor cement. J Periodontol 2000 Jan;71(1):8-13. [ ABSTRACT ]

Gamal AY, Maithot JM. The effect of local delivery of PDGF-BB on attachment of human periodontal ligament fibroblasts to periodontitis-affected root surfaces--in vitro. J Clin Periodontol 2000 May;27(5):347-53. [ ABSTRACT ]

Hobbs HC, Rowe DJ, Johnson PW. Periodontal ligament cells from insulin-dependent diabetics exhibit altered alkaline phosphatase activity in response to growth factors. J Periodontol 1999 Jul;70(7):736-42. [ ABSTRACT ]

Jiang D, Dziak R, Lynch SE, Stephan EB. Modification of an osteoconductive anorganic bovine bone mineral matrix with growth factors. J Periodontol 1999;70:834-9. [ ABSTRACT ]

Gamal AY, Mailhot JM, Garnick JJ, Newhouse R, Sharawy MM. Human periodontal ligament fibroblast response to PDGF-BB and IGF-1 application on tetracycline HCI conditioned root surfaces. J Clin Periodontol 1998 May;25(5):404-12. [ ABSTRACT ]

Howell TH, Fiorellini JP, Paquette DW, Offenbacher S, Giannobile WV and Lynch SE. A phase I/II clinical trial to evaluate a combination of recombinant human platelet derived growth factor-BB and recombinant human insulin-like growth factor-I in patients with periodontal disease. J Periodontol 1997 Dec;68(12):1 186-93. [ ABSTRACT ]

Bartold PM, Raben A. Growth factor modulation of fibroblasts in simulated wound healing. J Periodontal Res 1996 Apr;31(3):205-16. [ ABSTRACT ]

Giannobile WV, Hernandez RA, Finkelman RD, Ryan S, Kiritsy CP, D'Andrea M and Lynch SE. Comparative effects of platelet-derived growth factor-BB and insulin-like growth factor-I, individually and in combination, on periodontal regeneration in Macaca fascicularis. J Periodontal Res 1996 Jul;31(5):301-12. [ ABSTRACT ]

Oates TW, Kose KN, Xie JF, Graves UT, Collins JM, Cochran DL. Receptor binding of PDGF-AA and PDGF-BB, and the modulation of PDGF receptors by TGF-beta, in human periodontal ligament cells. J Cell Physiol 1995 Mar;162(3):359-66. [ ABSTRACT ]

Cho MI, Lin WL, Genco RJ. Platelet-derived growth factor-modulated guided tissue regenerative therapy. J Periodontol 1995 Jun;66(6):522-30. [ ABSTRACT ]

Park JB, Matsuura M, Han KY, Norderyd 0, Un WL, Genco RJ, Cho MI. Periodontal regeneration in class III furcation defects of beagle dogs using guided tissue regenerative therapy with platelet- derived growth factor. J Periodontol 1995 Jun;66(6):462-77. [ ABSTRACT ]

Oates TW, Rouse CA, Cochran DL. Mitogenic effects of growth factors on human periodontal ligament cells in vitro. J Periodontol 1993 Feb;64(2):142-8. [ ABSTRACT ]
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