GEM 21S® Growth-factor Enhanced Matrix was developed utilizing innovative tissue engineering principles which combine a bioactive protein (highly purified recombinant human platelet-derived growth factor, rhPDGF-BB) with an osteoconductive matrix (beta tricalcium phosphate, β-TCP).

This completely synthetic grafting system is engineered to stimulate wound healing and bone regeneration by triggering a cascade of molecular events when implanted into the body that continues on even after the implanted PDGF is gone.