Transverse section of core biopsy obtained 3 years post-surgery. Dense cortical bone with vascular channels is seen surrounding few remaining Bio-Oss (light brown) particles (8x).
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Regenerative Therapies in Implantology

Increasingly both aesthetic and functional factors must be considered prior to implant placement, especially in the aesthetic zones. Frequently, bone augmentation is required, either prior to or simultaneous with implant placement. The use of bone graft substitutes and barrier membranes has become the standard of care for treatment of bony defects in preparation for implant placement.

Bio-Oss® in implantology - Properties

  • Stabilization of the blood clot
  • Promotion of bone regeneration through the natural, osteoconductive mineral structure
  • Support of soft-tissue aesthetics by formation of a stable, bony base
  • Long-term maintenance of the regenerative volume by protection from resorption
Bio-Gide® in implantology - Properties
  • Efficient barrier against ingrowth of soft tissue into the defect
  • Good wound healing through natural three-dimensional support for overlying soft tissue flaps
  • Simplified soft-tissue management through reduction of post-operative wound dehiscence problems.

Indications for Bio-Oss® and Bio-Gide®

Indications for Bio-Oss®

  • Augmentation or reconstructive treatment of the alveolar ridge
  • Filling of extraction sockets to enhance preservation of the alveolar ridge
  • Elevation of the maxillary sinus floor
  • Filling of peri-implant defects in conjunction with products intended for Guided Bone Regeneration

Indications for Bio-Gide®

  • Simultaneous use of GBR-membrane (Bio-Gide®) and implants
  • Augmentation around implants placed in immediate or delayed extraction sockets
  • Localized ridge augmentation for later implantation
  • Alveolar ridge reconstruction for prosthetic treatment
  • Filling of bone defects after root resection, cystectomy, removal of retained teeth
  • Guided bone regeneration in dehiscence defects

Because of its malleability Bio-Gide® should be used in combination with a space making graft such as Bio-Oss®.
Bone regeneration in immediate implantation
Dr. Ch. Hämmerle, Zurich University
Bone defect associated with implantation Defect filling with Bio-Oss®
Covering with Bio-Gide® membrane
Re-Opening after 8 months
Ridge augmentation for later implantation
C. Maiorana, Milan University
Augmentation with Bio-Oss®
Occlusal view following tooth extraction
Initial clinical situation after extraction of the periodontally damaged teeth
Covering with Bio-Gide®
Insertion of implants into regenerated bone 6 months post-operatively
Implant Dehiscence
Dr. Thomas Balshi
Exposed implant threads covered with Bio-Oss® graft.
Immediate implant placed. Note large dehiscence with exposed threads.
Large buccal dehiscence following extraction of tooth #5.
Bio-Gide® resorbable membrane placed over Bio-Oss® graft.
Six month post implant & graft placement. Note bone completely covering implant.
Implants with abutments successfully integrated with surrounding bone.
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